Dasatinib-induced chylothorax beyond 5 years of treatment: is there actually any limit?

Dasatinib-induced chylothorax beyond 5 years of treatment: is there actually any limit?

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Dasatinib is a tyrosine kinase inhibitor used for treatment of some specific types of leukaemia.The development of pleural effusion is galaxy buds skin a known adverse effect of dasatinib and chylothorax is exceptional.No case has been reported beyond 5 years of treatment and extensive search for an alternative diagnosis is currently suggested in such scenario.The underlying mechanism is not currently clear.We describe a woman on dasatinib treatment for more than 10 years who developed catherine lansfield ombre rainbow clouds eyelet curtains chylothorax.

Drug withdrawal resolved the chylous pleural effusion.We were able to find 14 additional cases of dasatinib-related chylothorax reported up until now.